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HELLP syndrome occurs in about 0.7% of pregnancies and affects about 15% of women with eclampsia or severe pre-eclampsia. [5] [2] Death of the mother is uncommon (< 1%). [1] [3] Outcomes in the babies are generally related to how premature they are at birth. [1] The syndrome was first named in 1982 by American gynaecologist Louis Weinstein. [2]
Eclampsia is the onset of seizures (convulsions) in a woman with pre-eclampsia. [1] Pre-eclampsia is a hypertensive disorder of pregnancy that presents with three main features: new onset of high blood pressure, large amounts of protein in the urine or other organ dysfunction, and edema.
A high-risk pregnancy is a pregnancy where the mother or the fetus has an increased risk of adverse outcomes compared to uncomplicated pregnancies. No concrete guidelines currently exist for distinguishing “high-risk” pregnancies from “low-risk” pregnancies; however, there are certain studied conditions that have been shown to put the mother or fetus at a higher risk of poor outcomes. [1]
HELLP Syndrome is a type of preeclampsia with severe features that involves increased hemolysis, increased liver enzymes, and low platelet levels. [16] While most women with HELLP syndrome have high blood pressure and proteinuria, up to 20% of HELLP syndrome cases do not present with these classical signs of preeclampsia. [17]
In the immediate postpartum period (puerperium), 87% to 94% of women report at least one health problem. [8] [9] Long-term health problems (persisting after six months postpartum) are reported by 31% of women. [10] In 2016, complications of pregnancy, childbirth, and the puerperium resulted globally in 230,600 deaths, down from 377,000 deaths ...
HELLP syndrome is defined as hemolysis (microangiopathic), elevated liver enzymes (liver dysfunction), and low platelets (thrombocytopenia). This condition may occur in 10–20% of patients with severe pre-eclampsia and eclampsia [ 15 ] and is associated with increased maternal and fetal morbidity and mortality.
HELLP: HELLP syndrome (Hemolysis, elevated liver enzymes, low platelets in pregnancy) HEMA: hydroxy ethyl methacrylate, a material in soft contact lenses: Hema: hematest – e.g. hema (-) – fecal occult blood: HES: hydroxyethyl starch: HETE: hydroxyeicosatetraenoic acid: HEV: hepatitis E virus: HF: heart failure: HFpEF: heart failure with ...
In pregnant women, preeclampsia may occur after 20 weeks of pregnancy, often in women who have no history of high blood pressure. Symptoms of preeclampsia may include severe headache, vision changes and pain under the ribs. [45] However, in some women, symptoms may not occur, until they go for a routine prenatal visit. [46]