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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
The first reported case was in 1878 by Silas Weir Mitchell who suggested the term erythromelalgia to describe a syndrome of red congestion and burning pain in the hands and feet. [49] [50] Silas Weir Mitchell. He distinguished it from the painful red limbs seen in some patients with gout or rheumatoid arthritis. [49]
Pain radiating up into the leg, [1] behind the shin, and down into the arch, heel, and toes; Hot and cold sensations in the feet; A feeling as though the feet do not have enough padding; Pain while operating automobiles; Pain along the posterior tibial nerve path; Burning sensation on the bottom of foot that radiates upward reaching the knee
Clogs aren’t generally the best if you’re looking for a pair of shoes to take on long walks, as the backless design forces your toes to grip the sole to keep the foot stable.
The most common cause of foot pain is wearing ill fitting shoes. Women often wear tight shoes that are narrow and constrictive, and thus are most prone to foot problems. Tight shoes often cause overcrowding of toes and result in a variety of structural defects. The next most common cause of foot disease is overuse or traumatic injuries. [3]
[7]: 52 The toes also need vertical space; a toe cap which is low enough to press on the top of the toe may also cause bruising under the nail, especially if the toe cap is stiff. If the toebox is pointed, the toes may be wedged forwards into the area with inadequate height. [7]: 52–53, 135
It results in pain in the heel and bottom of the foot that is usually most severe with the first steps of the day or following a period of rest. [2] [4] Pain is also frequently brought on by bending the foot and toes up towards the shin. [3] [4] The pain typically comes on gradually, and it affects both feet in about one-third of cases. [2] [3]
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