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India has the highest rate of human rabies in the world, primarily because of stray dogs, [109] whose number has greatly increased since a 2001 law forbade the killing of dogs. [110] Effective control and treatment of rabies in India is hindered by a form of mass hysteria known as puppy pregnancy syndrome (PPS).
On a global scale, however, the World Health Organization reports that dogs are the main source of human rabies deaths, contributing up to 99% of all rabies transmissions to humans. Rabies is ...
After exposure to rabies, there is no contraindication to its use, because the untreated virus is virtually 100% fatal. [11] [13] The first rabies vaccine was introduced in 1885 and was followed by an improved version in 1908. [14] Over 29 million people worldwide receive human rabies vaccine annually. [15]
Canine mediated human rabies has been eliminated since 1980, and lyssaviruses have not been found in bat populations since 1954. [99] The last human death due to rabies occurred in 1980 (following a dog bite), [100] while the last case of rabies detected in a dog was in 2011. [101] Rabies was detected in a fox in 2018. [102]
From 1962 to 2022 there have been 157 recorded cases of the infection in United States, only 4 of those 157 individuals survived the disease. A combination of drugs have shown effectiveness in survivors. [11] Glanders, septicemic: Bacterial Untreated 95% The rate drops significantly to >50% with treatment. [12]
Rabies virus is estimated to cause around 55,000 deaths per year across the world [13] and has a death rate of nearly 100%. [14] These statistics coupled with the fact that there is currently no specific treatment, or antiviral drug [ 13 ] makes research on the virus of vital importance for the scientific community in order to possibly lower ...
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Lyssavirus (from the Greek λύσσα lyssa "rage, fury, rabies" and the Latin vīrus) [1] [2] is a genus of RNA viruses in the family Rhabdoviridae, order Mononegavirales. Mammals, including humans, can serve as natural hosts. [3] [4] The genus Lyssavirus includes the causative agent (rabies virus) of rabies. [5]