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Ofloxacin for systemic use is available in multiple strengths as a tablet, an oral suspension, and an injectable solution. It is also used as eye drops and ear drops and is available in combination with ornidazole. [66]
It is used as ear drops. [ 1 ] Ciprofloxacin, a fluoroquinolone antibiotic , has shown in vitro activity against many Gram-positive and Gram-negative bacteria including Staphylococcus aureus , Streptococcus pneumoniae , Haemophilus influenzae , Moraxella catarrhalis , and Pseudomonas aeruginosa .
Ear drops should not be shared to prevent the spread of infection. [7] Ear drops should not be used after the expiration date. [7] Ear drops should only be used in the affected ear. Ear drops are usually used for a short duration of time. Make sure to only use it as prescribed. [7]
Finafloxacin is used to treat a type of ear infection called acute otitis externa caused by Pseudomonas aeruginosa and Staphylococcus aureus bacteria. [3] In the clinical trial that led to the drug's approval, finafloxacin shortened the time to cessation of ear pain from an average of 6.8 days in patients taking a placebo to 3.5 days.
It can be taken by mouth, as eye drops, as ear drops, or intravenously. [5] [6] Common side effects include nausea, vomiting, and diarrhea. [5] Severe side effects include an increased risk of tendon rupture, hallucinations, and nerve damage. [5] In people with myasthenia gravis, there is worsening muscle weakness. [5]
Gatifloxacin is currently available in the US and Canada only as an ophthalmic solution. [citation needed] In 2011, the Union Health and Family Welfare Ministry of India banned the manufacture, sale, and distribution of gatifloxacin because of its adverse side effects. [8] In China, gatifloxacin is sold in tablet as well as in eye drop ...