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With treatment, many people with Polycythemia vera (PV) will live at least 14 years after diagnosis. The younger you are, the better your outlook, though other factors can also affect life...
Recent studies estimate the average life expectancy after diagnosis with polycythemia vera to be about 20 years. The average age of death is about 77. The most common cause of death is complications from blood clots (about 33%). Advancing cancer is the second most common cause (15%).
People with polycythemia vera have a shorter-than-average life expectancy, but timely treatment can improve a person's outlook and prevent complications.
Here, we give an overview of the developing prognostic tools and therapeutic landscape for PV, focusing on four drug classes: pegylated interferon-alpha 2, MDM2 antagonists, hepcidin mimetics, and histone deacetylase inhibitors. Keywords: Polycythemia vera, myeloproliferative neoplasm, treatment, prognostic tools.
This topic discusses treatment and prognosis of PV and secondary polycythemia. Discussed separately are: Evaluation of the patient with erythrocytosis. (See "Diagnostic approach to the patient with erythrocytosis/polycythemia".)
If you are not treated for polycythemia vera, it can lead to death within months or years, but you can survive for longer. The exact survival with polycythemia vera without treatment is not known. A person may survive for many years if complications do not occur.
For polycythemia vera, questions to ask your doctor include: What's the most likely cause of my symptoms? What tests do I need? Is this condition temporary, or will I always have it? What treatments are available, and which do you recommend? I have other health conditions. How can I best manage them together? Should I see a specialist?
Prognosis |. Key Points. Polycythemia vera is a chronic myeloproliferative neoplasm characterized by an increase in morphologically normal red cells (its hallmark), but also white cells and platelets. Ten to 15% of patients eventually develop myelofibrosis and bone marrow failure; acute leukemia occurs spontaneously in 1.0 to 2.5%.
The average life expectancy with polycythemia vera is 20 years after diagnosis. Is polycythemia vera cancer curable? There’s no cure for polycythemia vera, but it can be managed with...
Causes. Risk factors. Complications. Overview. Polycythemia vera (pol-e-sy-THEE-me-uh VEER-uh) is a type of blood cancer. It causes your bone marrow to make too many red blood cells. These excess cells thicken your blood, slowing its flow, which may cause serious problems, such as blood clots. Polycythemia vera is rare.