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  2. Ribosome-binding site - Wikipedia

    en.wikipedia.org/wiki/Ribosome-binding_site

    A ribosome binding site, or ribosomal binding site (RBS), is a sequence of nucleotides upstream of the start codon of an mRNA transcript that is responsible for the recruitment of a ribosome during the initiation of translation. Mostly, RBS refers to bacterial sequences, although internal ribosome entry sites (IRES) have been described in mRNAs ...

  3. Shine–Dalgarno sequence - Wikipedia

    en.wikipedia.org/wiki/Shine–Dalgarno_sequence

    Shine–Dalgarno sequence. The Shine–Dalgarno (SD) sequence is a ribosomal binding site in bacterial and archaeal messenger RNA, generally located around 8 bases upstream of the start codon AUG. [1] The RNA sequence helps recruit the ribosome to the messenger RNA (mRNA) to initiate protein synthesis by aligning the ribosome with the start codon.

  4. Ribosomal RNA - Wikipedia

    en.wikipedia.org/wiki/Ribosomal_RNA

    Ribosomal RNA is the predominant form of RNA found in most cells; it makes up about 80% of cellular RNA despite never being translated into proteins itself. Ribosomes are composed of approximately 60% rRNA and 40% ribosomal proteins, though this ratio differs between prokaryotes and eukaryotes. [ 2 ][ 3 ]

  5. Start codon - Wikipedia

    en.wikipedia.org/wiki/Start_codon

    In this genomic region, the two genes overlap. The start codon is the first codon of a messenger RNA (mRNA) transcript translated by a ribosome. The start codon always codes for methionine in eukaryotes and archaea and a N-formylmethionine (fMet) in bacteria, mitochondria and plastids. The start codon is often preceded by a 5' untranslated ...

  6. Eukaryotic translation - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_translation

    The ribosome can localize to the start site by direct binding, initiation factors, and/or ITAFs (IRES trans-acting factors) bypassing the need to scan the entire 5' UTR. This method of translation is important in conditions that require the translation of specific mRNAs during cellular stress, when overall translation is reduced.

  7. Ribosome - Wikipedia

    en.wikipedia.org/wiki/Ribosome

    Affinity label for the tRNA binding sites on the E. coli ribosome allowed the identification of A and P site proteins most likely associated with the peptidyltransferase activity; [5] labelled proteins are L27, L14, L15, L16, L2; at least L27 is located at the donor site, as shown by E. Collatz and A.P. Czernilofsky.

  8. Ribosomal protein - Wikipedia

    en.wikipedia.org/wiki/Ribosomal_protein

    A ribosomal protein (r-protein or rProtein[1][2][3]) is any of the proteins that, in conjunction with rRNA, make up the ribosomal subunits involved in the cellular process of translation. E. coli, other bacteria and Archaea have a 30S small subunit and a 50S large subunit, whereas humans and yeasts have a 40S small subunit and a 60S large ...

  9. Five prime untranslated region - Wikipedia

    en.wikipedia.org/wiki/Five_prime_untranslated_region

    Five prime untranslated region. The 5′ untranslated region (also known as 5′ UTR, leader sequence, transcript leader, or leader RNA) is the region of a messenger RNA (mRNA) that is directly upstream from the initiation codon. This region is important for the regulation of translation of a transcript by differing mechanisms in viruses ...