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This little-known but serious issue can be overcome by using an accuracy measure based on the logarithm of the accuracy ratio (the ratio of the predicted to actual value), given by (). This approach leads to superior statistical properties and also leads to predictions which can be interpreted in terms of the geometric mean.
If a main application of the forecast is to predict when certain thresholds will be crossed, one possible way of assessing the forecast is to use the timing-error—the difference in time between when the outcome crosses the threshold and when the forecast does so.
where is the actual value of the quantity being forecast, is the forecast, and is the number of different times for which the variable is forecast. Because actual rather than absolute values of the forecast errors are used in the formula, positive and negative forecast errors can offset each other; as a result, the formula can be used as a ...
where A t is the actual value and F t is the forecast value. The absolute difference between A t and F t is divided by half the sum of absolute values of the actual value A t and the forecast value F t. The value of this calculation is summed for every fitted point t and divided again by the number of fitted points n.
In bioinformatics, the root mean square deviation of atomic positions is the measure of the average distance between the atoms of superimposed proteins. In structure based drug design, the RMSD is a measure of the difference between a crystal conformation of the ligand conformation and a docking prediction.
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The MSE either assesses the quality of a predictor (i.e., a function mapping arbitrary inputs to a sample of values of some random variable), or of an estimator (i.e., a mathematical function mapping a sample of data to an estimate of a parameter of the population from which the data is sampled).