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Conjugated estrogens was introduced for medical use under the brand name Premarin in Canada in 1941, in the United States in 1942, and in the United Kingdom in 1956. [80] The manufacturer of Premarin secretly paid gynecologist Robert A. Wilson to promote its use by menopausal women in his 1966 book, Feminine Forever, leading to increased sales ...
Conjugated estrogens/methyltestosterone (CEEs/MT), sold under the brand name Premarin with Methyltestosterone, is a combination of conjugated estrogens (CEEs), an estrogen, and methyltestosterone (MT), an androgen and anabolic steroid (AAR), which is used in menopausal hormone therapy for women.
[275] [276] However, the available evidence overall does not support the use of estradiol and other estrogens for improving sexual desire and function in women as of 2016. [276] An exception is the use of estrogens to treat vaginal atrophy. [276] Estrogen therapy has been proposed as a potential treatment for autism but clinical studies are ...
Estrogen appears to have a protector effect on atherosclerosis: it lowers LDL and triglycerides, it raises HDL levels and has endothelial vasodilatation properties plus an anti-inflammatory component. Research is underway to determine if risks of estrogen supplement use are the same for all methods of delivery.
The estrogen receptor, as well as the progesterone receptor, have been detected in the skin, including in keratinocytes and fibroblasts. [ 25 ] [ 26 ] At menopause and thereafter, decreased levels of female sex hormones result in atrophy , thinning, and increased wrinkling of the skin and a reduction in skin elasticity , firmness, and strength.
Esterified estrogens (EEs), sold under the brand names Estratab and Menest among others, is an estrogen medication which is used hormone therapy for menopausal symptoms and low sex hormone levels in women, to treat breast cancer in both women and men, and to treat prostate cancer in men.
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