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Serum sickness in humans is a reaction to proteins in antiserum derived from a non-human animal source, occurring 5–10 days after exposure. Symptoms often include a rash , joint pain , fever , and lymphadenopathy .
It is also common to experience various sensations in the skin, from crawling or tingling sensations, tenderness of palms and the soles, and numbness of hands, arm, legs or feet. [10] Other skin reactions include skin rash, swelling and stinging sensation. [10] Suramin can also cause loss of appetite and irritability. [10]
Serum sickness–like reaction is named for its clinical similarity to serum sickness, in which immune complexes are deposited in the skin, joints, and other organs. True serum sickness, a type III hypersensitivity reaction, results in fever, lymphadenopathy, arthralgias, cutaneous eruptions, gastrointestinal disturbances, proteinuria, and ...
In immunology, the Arthus reaction (/ ˌ ɑːr ˈ tj uː s /) is a type of local type III hypersensitivity reaction.Type III hypersensitivity reactions are immune complex-mediated, and involve the deposition of antigen/antibody complexes mainly in the vascular walls, serosa (pleura, pericardium, synovium), and glomeruli.
Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity. [2] It was developed by Merck Sharp & Dohme in 1971, as MK647, after showing promise in a research project studying more potent chemical analogs of aspirin. [3]
While it’s challenging to remember what ingredients are ideal in a skincare product, there are harsh components that we know we don’t want such as parabens, phlates and synthetic fragrances ...