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Orthogonal ligand-protein pairs (also known as re-engineered ligand-receptor interfaces or re-engineered enzyme-substrate interactions) are a protein-ligand binding pair made to be independent of the original binding pair. This is done by taking a mutant protein (naturally occurring or selectively engineered), which is activated by a different ...
Several sets of orthogonal functions have become standard bases for approximating functions. For example, the sine functions sin nx and sin mx are orthogonal on the interval x ∈ ( − π , π ) {\displaystyle x\in (-\pi ,\pi )} when m ≠ n {\displaystyle m\neq n} and n and m are positive integers.
In biology, ecology, demography, epidemiology, and many other disciplines, the growth of a population, the spread of infectious disease, etc. can be fitted using the logistic function. In agriculture the inverted logistic sigmoid function (S-curve) is used to describe the relation between crop yield and growth factors. The blue figure was made ...
An Introduction to Orthogonal Polynomials. Gordon and Breach, New York. ISBN 0-677-04150-0. Chihara, Theodore Seio (2001). "45 years of orthogonal polynomials: a view from the wings". Proceedings of the Fifth International Symposium on Orthogonal Polynomials, Special Functions and their Applications (Patras, 1999).
The Staudinger ligation is a reaction developed by the Bertozzi group in 2000 that is based on the classic Staudinger reaction of azides with triarylphosphines. [15] It launched the field of bioorthogonal chemistry as the first reaction with completely abiotic functional groups although it is no longer as widely used.
In the theory of orthogonal functions, Lauricella's theorem provides a condition for checking the closure of a set of orthogonal functions, namely: . Theorem – A necessary and sufficient condition that a normal orthogonal set {} be closed is that the formal series for each function of a known closed normal orthogonal set {} in terms of {} converge in the mean to that function.
We say that functions and are orthogonal if their inner product (equivalently, the value of this integral) is zero: f , g w = 0. {\displaystyle \langle f,g\rangle _{w}=0.} Orthogonality of two functions with respect to one inner product does not imply orthogonality with respect to another inner product.
An example is the pair of sets of respectively left and right eigenvectors of a matrix, indexed by eigenvalue, if the eigenvalues are distinct. [ 1 ] A biorthogonal system in which E = F {\displaystyle E=F} and v ~ i = u ~ i {\displaystyle {\tilde {v}}_{i}={\tilde {u}}_{i}} is an orthonormal system .