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The Legend of Zelda: Tears of the Kingdom [b] is a 2023 action-adventure game developed and published by Nintendo for the Nintendo Switch.The player controls Link as he searches for Princess Zelda and fights to prevent Ganondorf from destroying Hyrule.
1q21.1 duplication syndrome arises from microduplications of the BP3-BP4 region, containing at least seven genes and a minimum duplicated region of ~1.2 Mb of unique DNA sequence. [ 7 ] 1q21.1 duplication syndrome has an autosomal dominant inheritance pattern, where 18–50% of deletions happen de novo and 50–82% are inherited from their parents.