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Digoxin (better known as Digitalis), sold under the brand name Lanoxin among others, is a medication used to treat various heart conditions. [4] Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. [4] Digoxin is one of the oldest medications used in the field of cardiology.
Digoxin immune Fab used to treat digoxin toxicity. The primary treatment of digoxin toxicity is digoxin immune fab, which is an antibody made up of anti-digoxin immunoglobulin fragments. This antidote has been shown to be highly effective in treating life-threatening signs of digoxin toxicity such as hyperkalemia, hemodynamic instability, and ...
Digitalis (/ ˌ d ɪ dʒ ɪ ˈ t eɪ l ɪ s / [3] or / ˌ d ɪ dʒ ɪ ˈ t æ l ɪ s / [4]) is a genus of about 20 species of herbaceous perennial plants, shrubs, and biennials, commonly called foxgloves. Digitalis is native to Europe, Western Asia, and northwestern Africa. The flowers are tubular in shape, produced on a tall spike, and vary in ...
Digoxin helps alleviate symptoms and reduce hospitalizations related to heart failure, but it does not offer any mortality-reducing benefits. [86] Digoxin may be considered in patients who remain symptomatic despite receiving treatment with a first-line combination of an ACE inhibitor (or ARNI ), a beta-blocker , and a mineralocorticoid ...
Digitalis purpurea, the foxglove or common foxglove, is a toxic species of flowering plant in the plantain family Plantaginaceae, [2] native to and widespread throughout most of temperate Europe. [3] It has also naturalized in parts of North America, as well as some other temperate regions.
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Digitalis lanata contains a powerful cardiac glycoside that may be used by patients with heart conditions. Digoxin (digitalin) is a drug that is extracted from D. lanata. [17] [18] It is used to treat some heart conditions such as atrial fibrillation and cardiac arrhythmias. [18]
The general structure of a cardiac glycoside consists of a steroid molecule attached to a sugar and an R group. [4] The steroid nucleus consists of four fused rings to which other functional groups such as methyl, hydroxyl, and aldehyde groups can be attached to influence the overall molecule's biological activity. [4]