Search results
Results From The WOW.Com Content Network
Printable version; Page information; ... This diagram uses embedded text that can be easily translated using a text editor. ... Mevalonate pathway: Width: 744. ...
A third mevalonate pathway variant found in Thermoplasma acidophilum, phosphorylates mevalonate at the 3-OH position followed by phosphorylation at the 5-OH position. The resulting metabolite, mevalonate-3,5-bisphosphate, is decarboxylated to IP, and finally phosphorylated to yield IPP (Archaeal Mevalonate Pathway II). [6] [7]
Printable version; In other projects ... Phosphomevalonic acid is an intermediate in the Mevalonate pathway. [1] Mevalonate pathway. (Phosphomevalonic acid labeled as ...
Mevalonate diphosphate decarboxylase catalyzes the final step in the mevalonate pathway. The mevalonate pathway is responsible for the biosynthesis of isoprenoids from acetate. [2] This pathway plays a key role in multiple cellular processes by synthesizing sterol isoprenoids, such as cholesterol, and non-sterol isoprenoids, such as dolichol ...
Print/export Download as PDF; Printable version; ... (or mevalonate-5-pyrophosphate, or 5-pyrophosphomevalonate) is an intermediate in the mevalonate pathway.
2 comments Toggle Annotating the mevalonate pathway and usage in 3 articles subsection
Mevalonate pathway Simplified version of the steroid synthesis pathway with the intermediates isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), geranyl pyrophosphate (GPP) and squalene. Some intermediates are omitted. The color scheme does not correctly represent the origins of the isoprene units of GPP.
In the final step of mevalonate biosynthesis, HMG-CoA reductase, an NADPH-dependent oxidoreductase, catalyzes the conversion of HMG-CoA into mevalonate, which is the primary regulatory point in this pathway. Mevalonate serves as the precursor to isoprenoid groups that are incorporated into a wide variety of end-products, including cholesterol ...