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Ethyl cyanohydroxyiminoacetate (oxyma) is the oxime of ethyl cyanoacetate and finds use as an additive for carbodiimides, such as dicyclohexylcarbodiimide (DCC) in peptide synthesis. It acts as a neutralizing reagent for the basicity or nucleophilicity of the DCC due to its pronounced acidity ( pKa 4.60) and suppresses base catalyzed side ...
Drug companies have made it harder to buy midazolam for executions. The etomidate was followed by rocuronium bromide, a paralytic, and finally, potassium acetate in place of the commonly used potassium chloride injection to stop the heart. Potassium acetate was first used for this purpose inadvertently in a 2015 execution in Oklahoma. [24]
In a reciprocating engine, the use of water injection, also called anti-detonation injection or ADI, is used to prevent engine knocking also known as "detonation". [3] Commonly found on large radial engines with pressure carburetors , it is a mixture of water and alcohol injected into the carburetor at high power settings.
Water for injection is generally made by distillation or reverse osmosis. [5] It should contain less than a mg of elements other than water per 100 ml. [5] Versions with agents that stop bacterial growth are also available. [5] In the UK, some hospitals offer subcutaneous injections of water directly for treating back pain in labour.
Intravenous administration, meaning injection into vein, is commonly used in most animals owing to its rapid speed to distribute the drug into the brain and its high reliability. [ 1 ] [ 2 ] Whilst there are alternatives like intraperitoneal injection which are less irritating, a larger dose of solution is required to euthanize the animals.
Ethyl cyanoacetate is a building block for the synthesis of heterocycles which are used for example as drugs: Allopurinol , used for the treatment of chronic gout, can be synthesized starting with a Knoevenagel condensation with triethyl orthoformate ; the condensation product is cyclized with hydrazine to give a substituted pyrazole and ...
Sodium 2-hydroxyethyl sulfonate (also: sodium isethionate) is the sodium salt of 2-hydroxyethane sulfonic acid (isethionic acid), it is used as a hydrophilic head group in washing-active surfactants, known as isethionates (acyloxyethanesulfonates) due to its strong polarity and resistance to multivalent ions.
Iodized oil, also known as ethiodized oil, brand name Lipiodol, is a medication derived from poppyseed oil and iodine.When given by injection, it is a radio-opaque contrast agent that is used to outline structures in radiological investigations.