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He co-founded the journal Tissue Engineering [19] and was the founding president of the Tissue Engineering Society (which evolved into TERMIS), co-founded in 1994 with Charles Vacanti, Joseph Upton of the Beth Israel Deaconess Medical Center and Harvard Medical School, Tony Atala of Boston Children’s Hospital, Mark Randolph of the ...
Micro-mass cultures of C3H-10T1/2 cells at varied oxygen tensions stained with Alcian blue. A commonly applied definition of tissue engineering, as stated by Langer [3] and Vacanti, [4] is "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve [Biological tissue] function or a ...
A major technology of regenerative medicine is tissue engineering, [2] which has variously been defined as "an interdisciplinary field that applies the principles of engineering and the life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function", or "the creation of new tissue by the ...
Biological engineering is a science-based discipline founded upon the biological sciences in the same way that chemical engineering, electrical engineering, and mechanical engineering [7] can be based upon chemistry, electricity and magnetism, and classical mechanics, respectively.
Charles Alfred "Chuck" [1] Vacanti (born 1950) is a researcher in tissue engineering [2] and stem cells and the Vandam/Covino Professor of Anesthesiology, Emeritus, at Harvard Medical School. [3] He is a former head of the Department of Anesthesiology at the University of Massachusetts and Brigham and Women’s Hospital , now retired.
On the other hand, the strict meaning of "tissue culture" refers to the culturing of tissue pieces, i.e. explant culture. Tissue culture is an important tool for the study of the biology of cells from multicellular organisms. It provides an in vitro model of the tissue in a well defined environment which can be easily manipulated and analysed ...
Nevertheless, even the best 3D culture models fail to mimic an organ's cellular properties in many aspects, [6] including tissue-to-tissue interfaces (e.g., epithelium and vascular endothelium), spatiotemporal gradients of chemicals, and the mechanically active microenvironments (e.g. arteries' vasoconstriction and vasodilator responses to ...
In 1998, about 30% of the US cotton and corn crops were also expected to be products of genetic engineering. [29] Genetic engineering in biotechnology stimulated hopes for both therapeutic proteins, drugs and biological organisms themselves, such as seeds, pesticides, engineered yeasts, and modified human cells for treating genetic diseases.