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Since the homozygous recessive individual can only pass on recessive alleles, the allele the individual in question passes on determines the phenotype of the offspring. [3] Thus, this test yields 2 possible situations: If any of the offspring produced express the recessive trait, the individual in question is heterozygous for the dominant ...
An individual that is homozygous-recessive for a particular trait carries two copies of the allele that codes for the recessive trait. This allele, often called the "recessive allele", is usually represented by the lowercase form of the letter used for the corresponding dominant trait (such as, with reference to the example above, "p" for the ...
Figure 1: Inheritance pattern of dominant (red) and recessive (white) phenotypes when each parent (1) is homozygous for either the dominant or recessive trait. All members of the F 1 generation are heterozygous and share the same dominant phenotype (2), while the F 2 generation exhibits a 6:2 ratio of dominant to recessive phenotypes (3).
For example, in the ABO blood group system, chemical modifications to a glycoprotein (the H antigen) on the surfaces of blood cells are controlled by three alleles, two of which are co-dominant to each other (I A, I B) and dominant over the recessive i at the ABO locus. The I A and I B alleles produce different modifications.
A simple example to illustrate genotype as distinct from phenotype is the flower colour in pea plants (see Gregor Mendel). There are three available genotypes, PP (homozygous dominant), Pp (heterozygous), and pp (homozygous recessive). All three have different genotypes but the first two have the same phenotype (purple) as distinct from the ...
Underdominance exists in situations where the heterozygotic genotype is inferior in fitness to either the dominant or recessive homozygotic genotype. Compared to examples of overdominance in actual populations, underdominance is considered more unstable [3] [4] and may lead to the fixation of either allele. [1] [5] [6]
In medical genetics, compound heterozygosity is the condition of having two or more heterogeneous recessive alleles at a particular locus that can cause genetic disease in a heterozygous state; that is, an organism is a compound heterozygote when it has two recessive alleles for the same gene, but with those two alleles being different from each other (for example, both alleles might be ...
In a dominant-recessive inheritance, an average of 25% are homozygous with the dominant trait, 50% are heterozygous showing the dominant trait in the phenotype (genetic carriers), 25% are homozygous with the recessive trait and therefore express the recessive trait in the phenotype. The genotypic ratio is 1: 2 : 1, and the phenotypic ratio is 3: 1.