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Müllerian anomalies can be part of a multiple malformation syndrome. [1] [3] Studies have estimated that Mullerian anomalies can affect between 4 percent and nearly 7 percent of the female population. [4] [5] Müllerian anomalies occur as a congenital malformation of the Müllerian ducts during embryogenesis.
Müllerian agenesis, also known as Müllerian aplasia, vaginal agenesis, or Mayer–Rokitansky–Küster–Hauser syndrome (MRKH syndrome), is a congenital malformation characterized by a failure of the Müllerian ducts to develop, resulting in a missing uterus and variable degrees of vaginal hypoplasia of its upper portion.
The American Fertility Society (now American Society of Reproductive Medicine) Classification distinguishes: Class I—Müllerian agenesis (absent uterus). This condition is represented by the hypoplasia or the agenesis (total absence) of the different parts of the uterus: Vaginal hypoplasia or agenesis; Cervical hypoplasia or agenesis
Anomalies that develop within the paramesonephric duct system continue to puzzle and fascinate obstetricians and gynecologists. The paramesonephric ducts play a critical role in the female reproductive tract and differentiate to form the uterine tubes, uterus, superior vagina as well as the uterine cervix.
Persistent Müllerian duct syndrome (PMDS) is the presence of Müllerian duct derivatives (fallopian tubes, uterus, and/or the upper part of the vagina) [1] in what would be considered a genetically and otherwise physically normal male. [2]
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Chromosomal anomalies have been associated with BRA in certain cases (chromosomes 1, 2, 5 and 21), but these anomalies were not inherited and have not been observed in subsequent cases. Additionally, neither extreme substance abuse or environmental factors (high power line, mercury, ground water issues, etc.) have been reported to be linked to ...
Multicystic dysplastic kidney (MCDK) is a condition that results from the malformation of the kidney during fetal development. The kidney consists of irregular cysts of varying sizes. Multicystic dysplastic kidney is a common type of renal cystic disease, and it is a cause of an abdominal mass in infants. [5]