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  2. Primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Primary_lateral_sclerosis

    Primary lateral sclerosis (PLS) usually presents with gradual-onset, progressive, lower-extremity stiffness and pain due to muscle spasticity. Onset is often asymmetrical. [ 2 ] Although the muscles do not appear to atrophy as in ALS (at least initially), the disabling aspect of PLS is muscle spasticity and cramping, and intense pain when those ...

  3. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or (in the United States) Lou Gehrig's disease (LGD), is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction. [3]

  4. List of people with motor neuron disease - Wikipedia

    en.wikipedia.org/wiki/List_of_people_with_motor...

    This includes amyotrophic lateral sclerosis (ALS), progressive bulbar palsy (PBP), pseudobulbar palsy, progressive muscular atrophy (PMA), primary lateral sclerosis (PLS), spinal muscular atrophy (SMA) and monomelic amyotrophy (MMA), as well as some rarer variants resembling ALS.

  5. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    [1] [2] They include amyotrophic lateral sclerosis (ALS), [3] [4] progressive bulbar palsy (PBP), pseudobulbar palsy, progressive muscular atrophy (PMA), primary lateral sclerosis (PLS), spinal muscular atrophy (SMA) and monomelic amyotrophy (MMA), as well as some rarer variants resembling ALS. Motor neuron diseases affect both children and ...

  6. Frontotemporal dementia - Wikipedia

    en.wikipedia.org/wiki/Frontotemporal_dementia

    The main subtypes of frontotemporal dementia are behavioral variant FTD (bvFTD), two variants of primary progressive aphasia – semantic dementia (svPPA) and progressive nonfluent aphasia (nfvPPA) [4] [18] – as well as FTD associated with amyotrophic lateral sclerosis (FTD–ALS or FTD-MND). [15]

  7. Jamie Lynn-Sigler's Honest Quotes About Living With Multiple ...

    www.aol.com/entertainment/jamie-lynn-siglers...

    The Sopranos alum Jamie-Lynn Sigler first opened up about her multiple sclerosis battle in 2016, nearly 15 years after she was diagnosed with the autoimmune disease at age 20. “I already had a ...

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