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The risk of VTE with estradiol/nomegestrol acetate birth control pills is under study. [11] Incidence of irregular vaginal bleeding may be higher with estradiol-containing birth control pills in relation to the fact that estradiol is a weaker estrogen than ethinylestradiol in the endometrium. [3]
Excess estrogen, such as from birth control pills, appears to increase cholesterol levels in bile and decrease gallbladder movement, which can lead to gallstones. [152] Progestins found in certain formulations of oral contraceptive pills can limit the effectiveness of weight training to increase muscle mass. [153]
Birth control pills are the most commonly prescribed hormonal treatment for hirsutism, as they prevent ovulation and decrease androgen production by the ovaries. Additionally, estrogen in the pills stimulates the liver to produce more of a protein that binds to androgens and reduces their activity.
However, Cadence OTC is working on an over-the-counter combination birth control pill called Zena, which contains both estrogen and progestin — it's just not FDA-approved. How does it work?
Researchers have discovered that rats given this hormone exhibited more behaviors associated with anxiety, compared to a more natural estrogen used in a more modern form of the contraceptive pill.
Wen: Birth control pills containing both estrogen and progestin are associated with a small risk of blood clots. But progestin-only pills like Opill are not associated with a higher risk of blood ...