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What it looks like: Fifth Disease is caused by Parvovirus B19 and presents with a red rash on the cheeks, arms, and legs that can last for several weeks. This condition occurs most often in children.
Fifth disease, also known as erythema infectiosum and slapped cheek syndrome, [3] is a common and contagious disease caused by infection with parvovirus B19. [4] This virus was discovered in 1975 and can cause other diseases besides fifth disease. [5] Fifth disease typically presents as a rash and is most common in children.
It is the classic cause of the childhood rash called fifth disease or erythema infectiosum, or "slapped face syndrome". [5] [6] The name comes from it being the fifth in a list of historical classifications of common skin rash illnesses in children. [7] The virus was discovered by chance in 1975 by Australian virologist Yvonne Cossart.
The virus is commonly known as Fifth Disease “because it was the fifth in a list of common childhood rash illnesses, which also included measles, scarlet fever, rubella and roseola,” says ...
The term childhood disease refers to disease that is contracted or becomes symptomatic before the age of 18 or 21 years old. Many of these diseases can also be contracted by adults. Some childhood diseases include:
In children, Fifth disease is typically mild — its most distinctive symptoms include a fever and respiratory symptoms, followed by a red rash on the cheeks, then a “lacy” rash on the rest of ...
B19 infection is often asymptomatic but can manifest in a variety of ways, including Fifth disease with its characteristic rash in children, persistent anemia in immunocompromised persons and in people who have underlying hemoglobinopathies, [20] transient aplastic crises, hydrops fetalis in pregnant women, and arthropathy. Human bocavirus 1 is ...
3.3 per 100,000 (adults), 50 per 100,000 (children) [90] Thrombotic thrombocytopenic purpura: ADAMTS13 autoantibodies Confirmed 1-2 per million [91] Antiphospholipid syndrome: Antiphospholipid antibodies Confirmed 40-50 per 100,000 [92] Paroxysmal nocturnal hemoglobinuria: None specific, mutation causes self-cells to become susceptible to ...