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Stomach cancer, also known as gastric cancer, is a malignant tumor of the stomach. It's a cancer that develops from the lining of the stomach . [ 10 ] Most cases of stomach cancers are gastric carcinomas , which can be divided into a number of subtypes, including gastric adenocarcinomas . [ 2 ]
Cancer of the stomach, also called gastric cancer, is the fourth-most-common type of cancer and the second-highest cause of cancer death globally. [2] Eastern Asia (China, Japan, Korea, Mongolia) is a high-risk area for gastric cancer, and North America, Australia, New Zealand and western and northern Africa are areas with low risk. [5]
The stomach is an organ of the gastrointestinal tract that sits in the abdomen. [1] Tumors of the stomach are known as gastric tumors, and can be either benign or malignant (gastric cancer). These tumors arise from the cells of the gastric mucosa which lines the stomach. Typically, most gastric tumors are cancerous and not detected until a ...
The adenoma, lacking the "carcinoma" attached to the end of it, suggests that it is a benign version of the malignant adenocarcinoma. The gastroenterologist uses a colonoscopy to find and remove these adenomas and polyps to prevent them from continuing to acquire genetic changes that will lead to an invasive adenocarcinoma.
The pattern of metastasis is different for gastric signet cell carcinoma than for intestinal-type gastric carcinoma. The SRCC tumor is often seen in the peritoneum and has also been known to spread to lymphatic permeation of the lungs and to the ovaries , creating Krukenberg tumors . [ 14 ]
Zolbetuximab is indicated in combination with fluoropyrimidine- and platinum-containing chemotherapy for the first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric or gastroesophageal junction adenocarcinoma whose tumors are claudin (CLDN) 18.2 positive ...
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