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CA19-9 can be elevated in many types of gastrointestinal cancer, such as colorectal cancer, esophageal cancer and hepatocellular carcinoma. [1] Apart from cancer, elevated levels may occur in pancreatitis, cirrhosis, [1] and diseases of the bile ducts. [1] [3] It can also be elevated in people with obstruction of the bile ducts. [3]
Tumor marker Associated tumor types Alpha fetoprotein (AFP) germ cell tumor, hepatocellular carcinoma [9] CA15-3: breast cancer [10] CA27.29: breast cancer [11] CA19-9: Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer. [12] CA-125
CA19-9 (carbohydrate antigen 19.9) is a tumor marker that is frequently elevated in pancreatic cancer. However, it lacks sensitivity and specificity, not least because 5% of people lack the Lewis (a) antigen and cannot produce CA19-9. It has a sensitivity of 80% and specificity of 73% in detecting pancreatic adenocarcinoma, and is used for ...
Levels of the tumor markers carbohydrate antigen 19-9 (CA 19–9), carcinoembryonic antigen (CEA) and CA 125 are abnormally high in the bloodstreams of patients with intrahepatic cholangiocarcinoma and Klatskin tumor. The serum CA 19–9 in particular may be very high. [10]
Examples of such prognostic biomarkers include elevated levels of metallopeptidase inhibitor 1 (TIMP1), a marker associated with more aggressive forms of multiple myeloma, [24] elevated estrogen receptor (ER) and/or progesterone receptor (PR) expression, markers associated with better overall survival in patients with breast cancer; [25] [26 ...
The objective of this study was to compare different tumor markers and their diagnostic value. The tumor markers tested in this experiment were CA 19-9, CA 242 and CEA tumor markers. The data revealed that although each marker have its own level of specificity and correspond to a cancer, all three makers together increase diagnostic value. [7]
Biomarkers found in blood, urine, or body tissues that can be introduced or elevated by the presence of one or more types of cancer. ... (tumor marker) CA19-9 ...
230099 Ensembl ENSG00000107159 ENSMUSG00000028463 UniProt Q16790 Q8VHB5 RefSeq (mRNA) NM_001216 NM_139305 RefSeq (protein) NP_001207 NP_647466 Location (UCSC) Chr 9: 35.67 – 35.68 Mb Chr 4: 43.51 – 43.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carbonic anhydrase IX (CA9/CA IX) is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase ...