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  2. Ataxia - Wikipedia

    en.wikipedia.org/wiki/Ataxia

    Ataxia (from Greek α- [a negative prefix] + -τάξις [order] = "lack of order") is a neurological sign consisting of lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements, that indicates dysfunction of parts of the nervous system that coordinate movement, such as the cerebellum.

  3. Geology of the Appalachians - Wikipedia

    en.wikipedia.org/wiki/Geology_of_the_Appalachians

    The northern end of the Appalachian Basin extends offshore into Lakes Erie and Ontario as far as the United States–Canada border. The province covers an area of about 185,500 square miles (480,000 km 2) and is 1,075 miles (1,730 km) long from northeast to southwest and between 20 and 310 miles (30 and 500 km) wide from northwest to southeast ...

  4. Costamere - Wikipedia

    en.wikipedia.org/wiki/Costamere

    The costamere is a structural-functional component of striated muscle cells [1] which connects the sarcomere of the muscle to the cell membrane (i.e. the sarcolemma). [ 2 ] Costameres are sub-sarcolemmal protein assemblies circumferentially aligned in register with the Z-disk of peripheral myofibrils .

  5. Sarcomere - Wikipedia

    en.wikipedia.org/wiki/Sarcomere

    A sarcomere (Greek σάρξ sarx "flesh", μέρος meros "part") is the smallest functional unit of striated muscle tissue. [1] It is the repeating unit between two Z-lines. Skeletal muscles are composed of tubular muscle cells (called muscle fibers or myofibers) which are formed during embryonic myogenesis.

  6. Skeletal muscle - Wikipedia

    en.wikipedia.org/wiki/Muscular

    [2] [3] The skeletal muscle cells are much longer than in the other types of muscle tissue, and are also known as muscle fibers. [4] The tissue of a skeletal muscle is striated – having a striped appearance due to the arrangement of the sarcomeres. A skeletal muscle contains multiple fascicles – bundles of muscle fibers.

  7. Muscular system - Wikipedia

    en.wikipedia.org/wiki/Muscular_system

    Skeletal muscle, is a type of striated muscle, composed of muscle cells, called muscle fibers, which are in turn composed of myofibrils. Myofibrils are composed of sarcomeres, the basic building blocks of striated muscle tissue. Upon stimulation by an action potential, skeletal muscles perform a coordinated contraction by shortening each sarcomere.

  8. Dystrophin - Wikipedia

    en.wikipedia.org/wiki/Dystrophin

    In humans, the DMD gene is located on the short (p) arm of the X chromosome between positions 21.2 and 21.1. Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane.

  9. Lateral force transmission in skeletal muscle - Wikipedia

    en.wikipedia.org/wiki/Lateral_Force_Transmission...

    Muscles contain far more perimysial than endomysial connective tissue, and it has also been observed that the ratio of the dry mass of perimysium to that of endomysium ranges between 2.8-1 and 64–1. [13] The anatomical arrangement of the connective tissue at each level of organization influences the function of the muscle.