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Leukocyte esterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyte esterase test (LE test) is a urine test for the presence of white blood cells and other abnormalities associated with infection. White blood cells in the urine can indicate a urinary tract infection (UTI). Positive test results may ...
Reference ranges for urine tests are described below: Measurement Lower limit Upper limit Unit Urinary specific gravity: 1.003 [1] [2] 1.030 [1 ... Leukocytes: n/a: 0 ...
Urinalysis, a portmanteau of the words urine and analysis, [1] is a panel of medical tests that includes physical (macroscopic) ... Leukocyte esterase, ...
The urine test strip reaction is based on the action of leukocyte esterase in catalysing the hydrolysis of an ester of indolecarboxylic acid. The indoxyl that is liberated combines with a diazonium salt in order to produce a violet coloured azole dye. [21] 1) Reaction catalysed by leukocyte esterase
In the elderly, the leukocyte esterase test is often positive even in the absence of an infection. [citation needed] The urine dipstick test is readily available and provides fast, but often unreliable results. Some organisms such as chlamydia and Ureaplasma urealyticum will produce a negative leukocyte esterase reaction.
The analysis of urine is a valuable diagnostic tool because its composition reflects the functioning of many body systems, particularly the kidneys and urinary system, and specimens are easy to obtain. [1] Common urine tests include the routine urinalysis, which examines the physical, chemical, and microscopic properties of the urine; urine ...
It is reasonable to obtain a urine culture in those with signs of systemic infection that may be unable to report urinary symptoms, such as when advanced dementia is present. [30] Systemic signs of infection include a fever or increase in temperature of more than 1.1 °C (2.0 °F) from usual, chills, and an increased white blood cell count. [30]
It has been arbitrarily assumed that a number of over 4-5 leukocytes in the field of vision of the microscope indicates leukocyturia. [ 4 ] At the moment, there are also quick test strips available, allowing after wetting a special diagnostic bar, the detection of granulocytes in the urine, as evidenced by the color change of the test strip. [ 5 ]