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Hidradenitis suppurativa (HS), sometimes known as acne inversa or Verneuil's disease, is a long-term dermatological condition characterized by the occurrence of inflamed and swollen lumps. [ 2 ] [ 3 ] These are typically painful and break open, releasing fluid or pus . [ 3 ]
A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...
Clascoterone is indicated for the topical treatment of acne vulgaris in people aged twelve years of age and older. [5] [13] Two large phase III randomized controlled trials evaluated the effectiveness of clascoterone for the treatment of acne over a period of 12 weeks. [5] [13] [14] Clascoterone decreased acne symptoms by about 8 to 18% more ...
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[67] [165] [166] [167] Treatment twice daily for six months is necessary, and is as effective as topical benzoyl peroxide 5%, isotretinoin 0.05%, and erythromycin 2%. [168] Azelaic acid is an effective acne treatment due to its ability to reduce skin cell accumulation in the follicle and its antibacterial and anti-inflammatory properties. [67]
Hidradenitis suppurativa is a chronic cutaneous condition originally thought to be primarily characterized by suppurative inflammation of the apocrine sweat glands. [ 3 ] : 710 Recent evidence supports that the primary event is follicular hyperkeratosis and obstruction, [ 4 ] but the term hidradenitis supperativa has continued to be used in ...
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