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Doxylamine succinate is the active ingredient in many over-the-counter sleep aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Doxepin is used in the treatment of insomnia. [11] In 2016, the American College of Physicians advised that insomnia be treated first by treating comorbid conditions, then with cognitive behavioral therapy and behavioral changes, and then with drugs; doxepin was among those recommended for short-term help maintaining sleep, on the basis of weak evidence.
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Effective first generation antihistamines include doxylamine, diphenhydramine, promethazine, meclizine, cyclizine, and cinnarizine. [2] In pregnancy meclizine, dimenhydrinate and doxylamine are generally felt to be safe. [2] Side effects include sleepiness. [2] [41] Second generation antihistamines have not been found to be useful. [2]
Excessive daytime sleepiness ... A proper diagnosis of the underlying cause and ultimately treatment of symptoms and/or the underlying cause can help mitigate such ...
All medications within the NyQuil imprint contain sedating antihistamines, hypnotics, and/or alcohol; they are intended to be taken before sleep. Its daytime counterpart is antihistamine-free DayQuil, formulated to avoid drowsiness. NyQuil is also used as a sleep aid. [1] NyQuil was first marketed in the United States in 1966. [2] [3]