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Exocrine pancreatic insufficiency (EPI) is the inability to properly digest food due to a lack or reduction of digestive enzymes made by the pancreas.EPI can occur in humans and is prevalent in many conditions [1] such as cystic fibrosis, [2] Shwachman–Diamond syndrome, [3] different types of pancreatitis, [4] multiple types of diabetes mellitus (Type 1 and Type 2 diabetes), [5] advanced ...
In addition to this, bile also plays a role in fat absorption, where dietary lipids are combined so that pancreatic lipases can hydrolyze them before going towards the small intestine. Without bile acids, this pathway would have a hard time occurring, which would lead to fat malabsorption and make steatorrhea more probable to occur. [ 2 ]
Damage to the pancreas can reduce the production of pancreatic enzymes that aid digestion, causing Exocrine Pancreatic Insufficiency. Fats and nutrients are not absorbed properly, leading to loose, greasy stool known as steatorrhea. It can also lead to malnutrition. [1] [2] Weight loss even when eating habits and amounts are normal. [1]
The symptoms most commonly associated with chronic pancreatitis, regardless of the cause, can include weight loss, diarrhea, and cramping. Accordingly, most people who have chronic pancreatitis ...
A pancreatic cyst is a fluid filled sac within the pancreas. They can be benign or malignant. X-ray computed tomography (CT scan) findings of cysts in the pancreas are common, and often are benign. In a study of 2,832 patients without pancreatic disease, 73 patients (2.6%) had cysts in the pancreas. [3] About 85% of these patients had a single ...
In chronic pancreatitis, weight loss, fatty stool, and diarrhea may occur. [1] [5] Complications may include infection, bleeding, diabetes mellitus, or problems with other organs. [1] The two most common causes of acute pancreatitis are a gallstone blocking the common bile duct after the pancreatic duct has joined; and heavy alcohol use. [1]
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