Search results
Results From The WOW.Com Content Network
The study concludes that bacteriophage preparations were safe and effective for treatment of chronic ear infections in humans. Additionally, there have been numerous animal and other experimental clinical trials evaluating the efficacy of bacteriophages for various diseases, such as infected burns and wounds, and cystic fibrosis-associated lung ...
Total phage representation in the virome is higher in individuals with Cardiovascular disease than healthy controls, totaling 63% and 18% respectively. [6] Lastly, researchers studying Colorectal cancer have observed increased richness in a variety of phage genera, with the most notable differences seen in Inovirus and Tunalikevirus. [13]
During 1962-1964 phage T4 researchers provided an opportunity to study the function of virtually all of the genes that are essential for growth of the phage under laboratory conditions. [43] [44] These studies were facilitated by the discovery of two classes of conditional lethal mutants. One class of such mutants is known as amber mutants. [45]
Phage injecting its genome into bacterial cell An electron micrograph of bacteriophages attached to a bacterial cell. These viruses are the size and shape of coliphage T1. Phage therapy, viral phage therapy, or phagotherapy is the therapeutic use of bacteriophages for the treatment of pathogenic bacterial infections.
the tendency of at least some phage to enter into (and then subsequently leave) a not very well understood state known (inconsistently) as pseudolysogeny [9] [10] Another way of envisioning phage "organismal" ecology is that it is the study of phage adaptations that contribute to phage survival and transmission to new hosts or environments.
Structural overview of T2 phage. Hershey and Chase needed to be able to examine different parts of the phages they were studying separately, so they needed to distinguish the phage subsections. Viruses were known to be composed of a protein shell and DNA, so they chose to uniquely label each with a different elemental isotope. This allowed each ...
The two ends of the phage are capped by a few copies of proteins that are important for infection of the host bacteria, and also for assembly of nascent phage particles. These proteins are the products of phage genes 3 and 6 at one end of the phage, and phage genes 7 and 9 at the other end.
Temperate phages (such as lambda phage) can reproduce using both the lytic and the lysogenic cycle. [4] How a phage decides which cycle to enter depends on a variety of factors. [5] For instance, if there are several other infecting phages (or if there is a high multiplicity), it is likely that the phage will use the lysogenic cycle.