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Lipid bilayers are complicated molecular systems with many degrees of freedom. Thus, atomistic simulation of membrane and in particular ab initio calculations of its properties is difficult and computationally expensive. Quantum chemical calculations has recently been successfully performed to estimate dipole and quadrupole moments of lipid ...
While unsaturated lipids may have more rigid individual bonds, membranes made with such lipids are more fluid because the individual lipids cannot pack as tightly as saturated lipids and thus have lower melting points: less thermal energy is required to achieve the same level of fluidity as membranes made with lipids with saturated hydrocarbon ...
Membrane lipids are a group of compounds (structurally similar to fats and oils) which form the lipid bilayer of the cell membrane. The three major classes of membrane lipids are phospholipids, glycolipids, and cholesterol. Lipids are amphiphilic: they have one end that is soluble in water ('polar') and an ending that is soluble in fat ...
In both phases the lipid molecules are constrained to the two dimensional plane of the membrane, but in liquid phase bilayers the molecules diffuse freely within this plane. Thus, in a liquid bilayer a given lipid will rapidly exchange locations with its neighbor millions of times a second and will, through the process of a random walk ...
An unsaturated fat is a fat or fatty acid in which there is at least ... This fatty acid composition results in a more fluid cell membrane but also one that is ...
Lipid peroxidation, or lipid oxidation, is a complex chemical process that leads to oxidative degradation of lipids, [1] resulting in the formation of peroxide and hydroperoxide derivatives. [2] It occurs when free radicals , specifically reactive oxygen species (ROS), interact with lipids within cell membranes , typically polyunsaturated fatty ...
Homeoviscous adaptation is the adaptation of the cell membrane lipid composition to keep the adequate membrane fluidity.. The maintenance of proper cell membrane fluidity is of critical importance for the function and integrity of the cell, essential for the mobility and function of embedded proteins and lipids, diffusion of proteins and other molecules laterally across the membrane for ...
An example is the endocannabinoids that are unsaturated fatty acid derivatives, which mainly are considered to be synthesised “on demand” from phospholipid precursors residing in the cell membrane, but may also be synthesised and stored in intracellular lipid droplets and released from those stores under appropriate conditions.