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Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [1] Complications may include seizures, cerebral palsy, or kernicterus. [1] In most of cases there is no specific underlying physiologic disorder. [2]
Like other forms of severe neonatal jaundice, there is the possibility of the neonate developing acute or chronic kernicterus, however the risk of kernicterus in HDN is higher because of the rapid and massive destruction of blood cells. Isoimmunization is a risk factor for neurotoxicity and lowers
Bilirubin should be tested from cord blood. [5] Ferritin - because most infants affected by HDN have iron overload, ferritin levels must be measured before giving the infant any additional iron. [11] Newborn Screening Tests - Transfusion with donor blood during pregnancy or shortly after birth can affect the results of the Newborn Screening Tests.
Neonatal cholestasis refers to elevated levels of conjugated bilirubin identified in newborn infants within the first few months of life. [1] Conjugated hyperbilirubinemia is clinically defined as >20% of total serum bilirubin or conjugated bilirubin concentration greater than 1.0 mg/dL regardless of total serum bilirubin concentration. [2]
After that, the risk of an IUT is greater than the risk from post birth transfusion. [31] Steroids - Steroids are sometimes given to the mother before IUTs and early delivery to mature the fetal lungs. [31] [32] Phenobarbital - Phenobarbital is sometimes given to the mother to help mature the fetal liver and reduce hyperbilirubinemia. [32] [33]
Several important factors that may predispose late-preterm infants to medical conditions associated with immaturity: [1] respiratory distress; apnea; temperature instability; hypoglycemia; hyperbilirubinemia; poor feeding; At 34–35 weeks, the brain weight is only about 2 ⁄ 3 that of a full-term baby. This may lead to an increased risk of ...
More information about potential risk factors that could affect the business and financial results of Natus is included in Natus' annual report on Form 10-K for the year ended December 31, 2011 ...
After that, the risk of an IUT is greater than the risk from post birth transfusion. [26] Steroids – steroids are sometimes given to the mother before IUTs and early delivery to mature the fetal lungs. [26] [14] Phenobarbital – Phenobarbital is sometimes given to the mother to help mature the fetal liver and reduce hyperbilirubinemia. [14] [27]