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Tretinoin (Retin-A®): Reduces inflammation and prevents clogged pores Adapalene (Differin®): Often less irritating than other retinoids, it’s sometimes prescribed to those with acne and ...
Adapalene, sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. [6] Studies have found adapalene is as effective as other retinoids, while causing less irritation. [7]
Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [ 8 ] [ 9 ] [ 10 ] For acne, it is applied to the skin as a cream, gel or ointment. [ 10 ]
Toxic effects of retinoids occur with both acute or prolonged intake, depending on which retinoid is considered. The specific toxicity is related to the mechanism of action as well as exposure. A medical sign of chronic or acute poisoning with retinol is hypervitaminosis A , which includes the presence of painful tender swellings on the long bones.
Side effects include increased skin photosensitivity, dryness, redness, and occasional peeling. [95] Sunscreen use is often advised during treatment, to prevent sunburn . Lower concentrations of benzoyl peroxide are just as effective as higher concentrations in treating acne but are associated with fewer side effects.
These adverse sexual side effects are typically seen in less than 5% of men on the drug. There is also a link to mental health effects, including depression. However, it’s unclear how common ...