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It contains fexofenadine, as the hydrochloride, an antihistamine; and pseudoephedrine, as the hydrochloride, a nasal decongestant. [ 2 ] In 2021, it was the 279th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.
The SPC is not intended to give general advice about treatment of a condition but does state how the product is to be used for a specific treatment. It forms the basis of information for health professionals to know how to use the specific product safely and effectively. The package leaflet supplied with the product is aimed at end-users. [3]
Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [11] Therapeutically, fexofenadine is a selective peripheral H 1 blocker.
Terfenadine acts as a peripherally-selective antihistamine, or antagonist of the histamine H 1 receptor. [3] It is a prodrug, generally completely metabolized to the active form fexofenadine in the liver by the enzyme cytochrome P450 3A4. Due to its near complete metabolism by the liver immediately after leaving the gut, terfenadine normally is ...
Upon study of records in mouse studies associated with 40 common medications ranging from antibiotics, antihistamines, aspirin, and hydrocortisone, that for subjects with melanoma and lung cancers, fexofenadine, one of three medications, along with loratadine, and cetirizine, that target histamine receptor H1 (HRH1), demonstrated significantly ...
An imperial fluid ounce is 1 ⁄ 20 of an imperial pint, 1 ⁄ 160 of an imperial gallon or exactly 28.4130625 mL. A US customary fluid ounce is 1 ⁄ 16 of a US liquid pint and 1 ⁄ 128 of a US liquid gallon or exactly 29.5735295625 mL, making it about 4.08% larger than the imperial fluid ounce. A US food labeling fluid ounce is exactly 30 mL.
Prior to the adoption of the unit of the minim in the early 19th century, the smallest unit of fluid measure in the Apothecaries' systems of the United States customary units and pre-1824 English units was, while inexact, presumed to be equal to 1 / 60 of a fluid dram or 1 / 480 of a fluid ounce.
2 fl dram or 8 mL [13] 1 ⁄ 4: 2 dessertspoons = 1 tablespoon tablespoon (mouthful) tbsp. or T., rarely tbls. 1 ⁄ 2 fluid ounce or 20 mL [10] most common size: 5 fl dr or 20 mL [17] 4 fluidrachm or 16 mL, [11] or 15 mL [18] (actual range: 12.8–15.6 mL [12]) 1/2 fl oz or 15 mL [13] [15] 1 ⁄ 2: 2 tablespoons = 1 handful handful (fluid ...