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Interleukin 7 (IL-7) is a protein [5] that in humans is encoded by the IL7 gene. [6] [7] [8] IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, [9] dendritic cells, [10] hepatocytes, [11] neurons, and epithelial cells, [12] but is not produced by normal ...
Composite deck boards are sold in either grooved or solid sided versions. The grooved composite board is fastened with hidden deck fasteners or clips, while the solid board is typically face-screwed. Most composite deck board manufacturers produce lengths of 12, 16, or 20 feet (3.7, 4.9, or 6.1 m), 5 + 1 ⁄ 2 by 3 ⁄ 4 inch (140 mm × 19 mm).
The nomenclature also proposes that IL-1F5 should be renamed to IL-36Ra, because it works as an antagonist to IL-36α, IL-36β and IL-36γ similar to how IL-1Ra works for IL-1α and IL-1β. Another revision was the renaming of IL-1F7 to IL-37 because this suppressing cytokine has many splicing variants , they should be called IL-37a, IL-37b and ...
IL-1R signalization activates immune response by activation of transcription of IL-1 target genes such as IL-6, IL-8, MCP-1, COX-2, IκBα, IL-1α, IL-1β, MKP-1. Components of signalization pathway of IL-1R which are involved in cellular response to IL-1 also mediate responses to other cytokines ( IL-18 and IL-33 ), Toll-like receptors (TLRs ...
The physiological activity determined from the dose dependent proliferation of murine D10S cells is 2.5 x 10 8 to 7.1 x 10 8 units/mg. IL-1β is present in other species of animals, however non-mammalian sequences of IL-1β lack a conserved cascase-1 cleavage site. [17] [18] [19]
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