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  2. Glucagon-like peptide-1 - Wikipedia

    en.wikipedia.org/wiki/Glucagon-like_peptide-1

    Active GLP-1 protein secondary structure includes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region. Alongside glucose-dependent insulinotropic peptide (GIP), GLP-1 is an incretin; thus, it has the ability to decrease blood sugar levels in a glucose-dependent manner by enhancing the secretion of insulin ...

  3. What Are GLP-1 Medications & Who Should Use Them? Here ... - AOL

    www.aol.com/glp-1-medications-them-heres...

    This means the GLP-1 levels from the medicine get much higher, which translates to better blood sugar and appetite control,” explains Spencer Nadolsky, D.O., an obesity and lipid specialist ...

  4. Whose cardiovascular health do SGLT2, GLP-1 diabetes ... - AOL

    www.aol.com/whose-cardiovascular-health-sglt2...

    dipeptidyl peptidase-4 (DPP-4) inhibitors — these help a person’s pancreas produce more insulin and less glucagon, to reduce their blood glucose levels. glucagon-like peptide-1 (GLP-1 ...

  5. Glucagon-like peptide-1 receptor - Wikipedia

    en.wikipedia.org/wiki/Glucagon-like_peptide-1...

    Exendin-4, an FDA-approved antidiabetic glucagon-like peptide 1 (GLP-1) receptor agonist, has been tested in mice with the mutated human huntingtin protein showing neurodegenerative changes, motor dysfunction, poor energy metabolism, and high blood glucose levels. Exendin-4 (Ex-4) treatment reduced the accumulation of mutated human huntingtin ...

  6. The Terrible—and Amazing—Side Effects of Weight-Loss Drugs

    www.aol.com/terrible-amazing-side-effects-weight...

    GLP-1s may be better than other diabetes drugs at helping with liver fat, according to a study published in 2023. Lower Blood Sugar Levels GLP-1s (you may remember) were developed as diabetes meds.

  7. GLP-1 receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GLP-1_receptor_agonist

    GLP-1 agonists were initially developed for type 2 diabetes. [7] The 2022 American Diabetes Association (ADA) standards of medical care in diabetes include GLP-1 agonists or SGLT2 inhibitors as a first-line pharmacological therapy for type 2 diabetes in patients who have or are at high risk for atherosclerotic cardiovascular disease or heart ...

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