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A bronchial challenge test is a medical test used to assist in the diagnosis of asthma. [1] The patient breathes in nebulized methacholine or histamine. Thus the test may also be called a methacholine challenge test or histamine challenge test respectively. Both drugs provoke bronchoconstriction, or narrowing of the airways.
Bear in mind, however, that this number does not apply to children, and that it can differ depending on the patient's native result; small patient's with pulmonary fibrosis, restrictive lung disease etc. will have a measurably lower FEV1 than healthy average-sized adults. This can give a false positive result of the test.
It is classically reduced in obstructive lung disorders such as asthma. Due to the wide range of 'normal' values and the high degree of variability, peak flow is not the recommended test to identify asthma. However, it can be useful in some circumstances. A small portion of people with asthma may benefit from regular peak flow monitoring. When ...
The International Olympic Committee recommends the eucapnic voluntary hyperventilation (EVH) challenge as the test to document exercise-induced asthma in Olympic athletes. [11] In the EVH challenge, the patient voluntarily, without exercising, rapidly breathes dry air enriched with 5% CO 2 for six minutes.
A PCP will ask questions in regards to symptoms and breathing; they will also ask if fatigue or wheezing has been experienced when breathing in or out; and also test using a peak expiratory flow and an oxygen saturation. Status asthmaticus can be misdiagnosed when wheezing occurs from an acute cause other than asthma. Some of these alternative ...
The role for eNO in other conditions is even less well established compared to asthma. Since asthma can be a cause of chronic coughing (it may even be the sole manifestation, such as in cough-variant asthma), studies have looked at whether eNO can be used in the diagnosis of chronic cough. [18] [19] [20] [21]
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