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The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products, [1] including catharanthine and vindoline [2] and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine [3] and vincristine, [4] all of which can be obtained from the plant.
This is a partial list of awareness ribbons. The meaning behind an awareness ribbon depends on its colors and pattern. Since many advocacy groups have adopted ribbons as symbols of support or awareness, ribbons, particularly those of a single color, some colors may refer to more than one cause. Some causes may be represented by more than one ...
Periwinkle blue is the color for esophageal and stomach cancer awareness ribbons, and for anorexia nervosa and bulimia. It is also the color for pulmonary hypertension awareness ribbons. [citation needed] Periwinkle was added to the Crayola palette in 1949. [6] In the late 1990s, the Anaheim Angels changed their uniform to include this color. [7]
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The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel diseaseBiological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [1]
Vinblastine is a vinca alkaloid [10] [3] [11] and a chemical analogue of vincristine. [12] [13] It binds tubulin, thereby inhibiting the assembly of microtubules. [14]Vinblastine treatment causes M phase specific cell cycle arrest by disrupting microtubule assembly and proper formation of the mitotic spindle and the kinetochore, each of which are necessary for the separation of chromosomes ...
Vinca difformis in habitat, Cáceres, Spain. Vinca plants are subshrubs or herbaceous, and have slender trailing stems 1–2 m (3 + 1 ⁄ 2 – 6 + 1 ⁄ 2 ft) long but not growing more than 20–70 cm (8– 27 + 1 ⁄ 2 in) above ground; the stems frequently take root where they touch the ground, enabling the plant to spread widely.