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  2. Baclofen - Wikipedia

    en.wikipedia.org/wiki/Baclofen

    Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]

  3. Intrathecal administration - Wikipedia

    en.wikipedia.org/wiki/Intrathecal_administration

    Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia, chemotherapy, or pain management. This route is also used to introduce drugs that fight ...

  4. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    Oral administration of a liquid. In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration ...

  5. Samidorphan - Wikipedia

    en.wikipedia.org/wiki/Samidorphan

    Routes of administration: By mouth: Pharmacokinetic data; Elimination half-life: 7–9 hours [1] [2] ... Development of baclofen/samidorphan has also been ...

  6. NYT ‘Connections’ Hints and Answers Today, Thursday, February 13

    www.aol.com/nyt-connections-hints-answers-today...

    Today's NYT Connections puzzle for Thursday, February 13, 2025The New York Times

  7. Drug - Wikipedia

    en.wikipedia.org/wiki/Drug

    The Food and Drug Administration (FDA) in the United States is a federal agency responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter medications, vaccines, biopharmaceuticals, blood transfusions, medical devices ...

  8. Tolperisone - Wikipedia

    en.wikipedia.org/wiki/Tolperisone

    Tolperisone is indicated for use in the treatment of pathologically increased tone of the skeletal muscle caused by neurological diseases (damage of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.

  9. Ziconotide - Wikipedia

    en.wikipedia.org/wiki/Ziconotide

    Ziconotide, sold under the brand name Prialt, also called intrathecal ziconotide (ITZ) because of its administration route, is an atypical analgesic agent for the amelioration of severe and chronic pain. Derived from Conus magus, a cone snail, it is the synthetic form of an ω-conotoxin peptide. [2]