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Budesonide/formoterol, sold under the brand name Symbicort among others, is a fixed-dose combination medication used in the management of asthma or chronic obstructive pulmonary disease (COPD). [2] It contains budesonide , a steroid ; and formoterol , a long-acting β 2 -agonist (LABA). [ 2 ]
Formoterol, also known as eformoterol, is a long-acting β 2 agonist (LABA) used as a bronchodilator in the management of asthma and chronic obstructive pulmonary disease (COPD). Formoterol has an extended duration of action (up to 12 h) compared to short-acting β 2 agonists such as salbutamol (albuterol
Drug Main indication ... 2017 2018 2019 1 adalimumab: rheumatoid arthritis: Humira 10.1 13.5 16.3 18.4 21.4 2 apixaban: anticoagulant: ... Symbicort: Budesonide ...
Viatris (VTRS) and its partner win a court decision that invalidates branded drug Symbicort's patent and opens the door for them to launch their generic version of the drug.
The plasma protein binding of budesonide is around 85-90%, with an apparent volume of distribution of 2.2-3.9L/kg. [49] [48] Budesonide is 80-90% metabolized at first pass in the liver by the hepatocytic cytochrome P450 isoenzyme 3A4 into two metabolites: 16 alpha-hydroxyprednisolone and 6 beta-hydroxybudesonide. Both of these metabolites have ...
Adults with mild type 2 diabetes might improve their insulin sensitivity by following a low-carb diet, thus potentially eliminating the need for medication, a new study suggests.