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  2. Pathophysiology of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of...

    Multiple sclerosis can be pathologically defined as the presence of distributed glial scars (or sclerosis) in the central nervous system disseminated in time (DIT) and space (DIS). [2] The gold standard for MS diagnosis is pathological correlation, though given its limited availability, other diagnosis methods are normally used. [ 3 ]

  3. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Pathology_of_multiple_sclerosis

    Multiple sclerosis (MS) can be pathologically defined as the presence of distributed glial scars in the central nervous system that must show dissemination in time (DIT) and in space (DIS) to be considered MS lesions. [1] [2] The scars that give the name to the condition are produced by the astrocyte cells attempting to heal old lesions. [3]

  4. Signs and symptoms of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    Main symptoms of multiple sclerosis Symptoms and findings in multiple sclerosis. Multiple sclerosis can cause a variety of symptoms varying significantly in severity and progression among individuals: changes in sensation (hypoesthesia), muscle weakness, abnormal muscle spasms, or difficulty moving; difficulties with coordination and balance; problems in speech or swallowing (), visual ...

  5. Lesional demyelinations of the central nervous system

    en.wikipedia.org/wiki/Lesional_demyelinations_of...

    Schilder disease or diffuse myelinoclastic sclerosis: is a rare disease that presents clinically as a pseudotumoural demyelinating lesion; and is more common in children. [7] [8] Marburg multiple sclerosis, an aggressive form, also known as malignant, fulminant or acute MS.

  6. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.

  7. Charcot's neurologic triad - Wikipedia

    en.wikipedia.org/wiki/Charcot's_neurologic_triad

    Multiple sclerosis Charcot's neurologic triad is the combination of nystagmus , intention tremor , and scanning or staccato speech . This triad is associated with multiple sclerosis , where it was first described; [ 1 ] however, it is not considered pathognomonic for it.

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