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Bio-layer interferometry (BLI) is an optical biosensing technology that analyzes biomolecular interactions in real-time without the need for fluorescent labeling. [1] Alongside Surface Plasmon Resonance , BLI is one of few widely available label-free biosensing technologies, a detection style that yields more information in less time than ...
Grating-coupled interferometry (GCI) is a biophysical characterization method mainly used in biochemistry and drug discovery for label-free analysis of molecular interactions. Similar to other optical methods such as surface plasmon resonance (SPR) or bio-layer interferometry (BLI), it is based on measuring refractive index changes within an ...
SCORE is especially used as detection method in bio- and chemosensors. It is a label-free technique like Reflectometric interference spectroscopy (RIfS), Bio-layer Interferometry (BLI) and Surface plasmon resonance (SPR), which allows time-resolved observation of binding events on the sensor surface without the use of fluorescence or radioactive labels.
Interferometry typically uses electromagnetic waves and is an important investigative technique in the fields of astronomy, fiber optics, engineering metrology, optical metrology, oceanography, seismology, spectroscopy (and its applications to chemistry), quantum mechanics, nuclear and particle physics, plasma physics, biomolecular interactions ...
Dual-polarization interferometry (DPI) is an analytical technique that probes molecular layers adsorbed to the surface of a waveguide using the evanescent wave of a laser beam. It is used to measure the conformational change in proteins, or other biomolecules, as they function (referred to as the conformation activity relationship ).
Interferometric microscopy or imaging interferometric microscopy is the concept of microscopy which is related to holography, synthetic-aperture imaging, and off-axis-dark-field illumination techniques.
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