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Choreoathetosis is the occurrence of involuntary movements in a combination of chorea (irregular migrating contractions) and athetosis (twisting and writhing).. It is caused by many different diseases and agents.
Chorea is characterized by brief, semi-directed, irregular movements that are not repetitive or rhythmic, but appear to flow from one muscle to the next. These 'dance-like' movements of chorea often occur with athetosis, which adds twisting and writhing movements. Walking may become difficult and include odd postures and leg movements.
Athetosis is a commonly occurring symptom in the disease cerebral palsy. [14] Of all people with the disease, between 16% [15] and 25% [4] of them actually exhibit the symptom of athetosis. A component of this is the finding that most often the symptoms that involve athetosis occur as a part of choreoathetosis as opposed to athetosis alone. [16]
The age at onset is between 1 and 20 years old. The attacks of involuntary movements last less than one minute and have a known trigger, usually a sudden voluntary movement. For example, if a PKD patient stands up or begins walking after being sedentary for a period of time, or a person goes from a walk to a run, it can trigger an attack.
Such contractile movements include dystonia, chorea, athetosis, and ballism. For example, “Her attacks were characterized as sudden unilateral stiffness of upper and lower limbs followed by an involuntary extrarotation of the arm and leg.” [ 3 ] Another frequently occurring symptom is the presence of an aura before the attack.
Choreoathetosis (CA) is characterized by hyperkinesia (chorea i.e. rapid involuntary, jerky, often fragmented movements) and hypokinesia (athetosis i.e. slower, constantly changing, writhing or contorting movements).
Chorea (rapid, involuntary movement) Drug induced chorea: G25.4 Drug-induced tics and tics of organic origin 333.3 G25.6 Paroxysmal nocturnal limb movement G25.80 Painful legs (or arms), moving toes (or fingers) syndrome G25.81 Sporadic restless leg syndrome: G25.82 Familial restless leg syndrome G25.83 Stiff-person syndrome: 333.91 G25.84
Hyperkinesia, more specifically chorea, is the hallmark symptom of Huntington's disease, formerly referred to as Huntington's chorea. Appropriately, chorea is derived from the Greek word, khoros, meaning "dance." The extent of the hyperkinesia exhibited in the disease can vary from solely the little finger to the entire body, resembling ...