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  2. Amitriptyline - Wikipedia

    en.wikipedia.org/wiki/Amitriptyline

    Amitriptyline is a highly lipophilic molecule having an octanol-water partition coefficient (pH 7.4) of 3.0, [132] while the log P of the free base was reported as 4. ...

  3. Tricyclic antidepressant overdose - Wikipedia

    en.wikipedia.org/wiki/Tricyclic_antidepressant...

    [16] [17] Another study reported 95% of deaths from antidepressants in England and Wales between 1993 and 1997 were associated with tricyclic antidepressants, particularly dothiepin and amitriptyline. It was determined there were 5.3 deaths per 100,000 prescriptions. [18]

  4. Tricyclic antidepressant - Wikipedia

    en.wikipedia.org/wiki/Tricyclic_antidepressant

    Several cases of the misuse [65] of amitriptyline alone [66] [67] or together with methadone [65] [68] or in other drug dependent patients [69] [70] and of dosulepin with alcohol [71] or in methadone patients [72] have been reported.

  5. Benzodiazepine overdose - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_overdose

    However, combinations of high doses of benzodiazepines with alcohol, barbiturates, opioids or tricyclic antidepressants are particularly dangerous, and may lead to severe complications such as coma or death. In 2013, benzodiazepines were involved in 31% of the estimated 22,767 deaths from prescription drug overdose in the United States. [5]

  6. Is drinking alcohol bad for your health? New dietary ...

    www.aol.com/drinking-alcohol-bad-health-dietary...

    Alcohol is a well-established, preventable cause of cancer responsible for about 100,000 cases of cancer and 20,000 cancer deaths annually in the United States – greater than the 13,500 ...

  7. Flupentixol/melitracen - Wikipedia

    en.wikipedia.org/wiki/Flupentixol/melitracen

    Adult: Per tablet contains flupentixol 0.5 mg and melitracen 10 mg: 1 tablet in the morning and at midday. May double morning dose in severe cases. Not to exceed 4 tablets daily. [citation needed] Elderly: Per tablet contains flupentixol 0.5 mg and melitracen 10 mg: 1 tablet in the morning. For severe cases: 1 tablet in the morning and at midday.