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Gene Designer is a computer software package for bioinformatics. [1] [2] It is used by molecular biologists from academia, government, and the pharmaceutical, chemical, agricultural, and biotechnology industries to design, [3] clone, and validate genetic sequences. It is proprietary software, released as freeware needing registration.
The ABRC's mission is to acquire, preserve and distribute seed and DNA resources that are useful to the Arabidopsis research community. TAIR’s community includes over 28,000 registered users [4] and the website draws about 60,000 unique visitors per month. [5] TAIR is located at Phoenix Bioinformatics, [6] and funded by subscriptions. [7]
OLIGO Primer Analysis Software is a software for DNA primer design. [ 1 ] [ 2 ] The first paper describing this software was published in 1989. [ 3 ] The program is a real time PCR primer and probe search and analysis tool.
Primer Premier is a bioinformatics software used for various PCR applications. It supports the design of degenerate primers for amplifying a related set of nucleotide sequences for the detection of common traits amongst organisms, as well as to determine heredity. [1] The software also designs tagged and nested primers for multiplex PCR ...
DNADynamo is a commercial DNA sequence analysis software package produced by Blue Tractor Software Ltd [1] that runs on Microsoft Windows, Mac OS X and Linux [2] It is used by molecular biologists [3] to analyze DNA and Protein sequences. A free demo is available from the software developers website.
Human, Mus musculus, Arabidopsis thaliana, Drosophila melanogaster [32] [33] mGene Support-vector machine (SVM) based system to find genes: Eukaryotes [34] mGene.ngs SVM based system to find genes using heterogeneous information: RNA-seq, tiling arrays: Eukaryotes [35] MORGAN: Decision tree system to find genes in vertebrate DNA: Eukaryotes [36 ...
The last 10-12 bases at the 3' end of a primer are sensitive to initiation of polymerase extension and general primer stability on the template binding site. The effect of a single mismatch at these last 10 bases at the 3' end of the primer depends on its position and local structure, reducing the primer binding, selectivity, and PCR efficiency.
Mesquite is a software package primarily designed for phylogenetic analyses. It was developed as a successor to MacClade, [1] when the authors recognized that implementing a modular architecture in MacClade would be infeasible. [2]