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DHEA can be lower in people with depression and after menopause, and levels tend to decrease as you age. At age 70 to 80 , DHEA levels may be down to 10 to 20 percent of those in a younger person.
Dehydroepiandrosterone sulfate, abbreviated as DHEA sulfate or DHEA-S, also known as androstenolone sulfate, is an endogenous androstane steroid that is produced by the adrenal cortex. [1] It is the 3β- sulfate ester and a metabolite of dehydroepiandrosterone (DHEA) and circulates in far greater relative concentrations than DHEA. [ 2 ]
Plasma levels of DHEA in adult men are 10 to 25 nM, in premenopausal women are 5 to 30 nM, and in postmenopausal women are 2 to 20 nM. [25] Conversely, DHEA-S levels are an order of magnitude higher at 1–10 μM. [25] Levels of DHEA and DHEA-S decline to the lower nanomolar and micromolar ranges in men and women aged 60 to 80 years. [25]
Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
But people who took 2,000 international units (IU) of vitamin D and did 30 minutes of strength training three times a week (in addition to the 1 gram of omega-3 fatty acids) saw an even greater ...
DHEA is an androgen precursor that lacks FDA and Health Canada approval for use in women, and is not available in Canada as a pharmaceutical preparation; [26] it is sold as an over-the-counter drug or incorporated into compounded preparations in the United States. In the body, it can be converted into testosterone then estrogen; there are no ...
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Those who cannot take DHEA because of the risk of hormonal-dependent cancer can take 7-Keto DHEA. With men who excessively aromatize testosterone, taking DHEA can lead to a simultaneous and undesirable increase in estradiol, a typically feminine estrogen. Replacing DHEA with 7-Keto DHEA will avoid this.