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Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2) are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
A U.K. coroner is pushing the country’s Food Standards Agency to upgrade its labeling of certain dietary supplements, after a man died in part from vitamin D toxicity, or hypervitaminosis D ...
There is no general agreement about the intake levels at which vitamin D may cause harm. According to the IOM review, "Doses below 10,000 IU/day are not usually associated with toxicity, whereas doses equal to or above 50,000 IU/day for several weeks or months are frequently associated with toxic side effects including documented hypercalcemia."
Excessive amounts or intake can result in weakness, headache, nausea, constipation, urinary tract infections, and abdominal pain. [7] [12] Serious side effects may include high blood calcium and anaphylaxis. [7] Calcitriol was identified as the active form of vitamin D in 1971 and the drug was approved for medical use in the United States in ...
Vitamin D3, aka cholecalciferol, is important for bone health and immune function. Experts discuss benefits, sources, risks and who needs a supplement. How to get the most out of vitamin D3
There's lots of confusion around the difference between vitamin D2 and vitamin D3, and which is best for whom. Doctors and experts explain.