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The game is set in a magical universe and deals with a fantasy school where players dress-up as royalty or supernatural creatures. [93] Launched in 2017, Royale High had more than 8.2 billion total visits as of October 2022, regularly achieving thousands of concurrent players, making it one of the most popular games on the platform. [94] [95]
Radiation-induced lumbar plexopathy (RILP) or radiation-induced lumbosacral plexopathy (RILSP) is nerve damage in the pelvis and lower spine area caused by therapeutic radiation treatments. RILP is a rare side effect of external beam radiation therapy [ 1 ] [ 2 ] [ 3 ] and both interstitial and intracavity brachytherapy radiation implants.
Side effects are dose-dependent; for example, higher doses of head and neck radiation can be associated with cardiovascular complications, thyroid dysfunction, and pituitary axis dysfunction. [15] Modern radiation therapy aims to reduce side effects to a minimum and to help the patient understand and deal with side effects that are unavoidable.
Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. [1] Symptoms can start within an hour of exposure, and can last for several months.
The process of removing a status effect varies. Some status effects expire after a certain amount of time has elapsed. Most games contain items capable of healing specific status effects, or rarer items which can heal all of them. Many games also include magic spells that can eliminate status effects.
The genetic effects of radiation, including the effects on cancer risk, were recognized much later. In 1927 Hermann Joseph Muller published research showing genetic effects, and in 1946 was awarded the Nobel prize for his findings. More generally, the 1930s saw attempts to develop a general model for radiobiology.
Bernard Fisher, among the first to conduct a clinical trial evaluating the efficacy of adjuvant therapy on patients with breast cancer, described it as a "value judgement" in which the potential benefits must be evaluated against the toxicity and cost of treatment and other potential side effects. [30] Often related to fear of side effects ...
[2] [1] Radiation proctitis most commonly occurs after pelvic radiation treatment for cancers such as cervical cancer, prostate cancer, bladder cancer, and rectal cancer. RAVE and chronic radiation proctopathy involves the lower intestine , primarily the sigmoid colon and the rectum, and was previously called chronic radiation proctitis, pelvic ...