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Red: notochord; Magenta: axochord; Green: nerve chord; Blue: epidermis; Yellow: mesoderm. The notochord is an elastic, rod-like structure found in chordates. In chordate vertebrates the notochord is an embryonic structure that disintegrates, as the vertebrae develop, to become the nucleus pulposus in the intervertebral discs of the vertebral ...
The lancelet notochord, unlike the vertebrate spine, extends into the head. This gives the subphylum, Cephalochordata, its name ( κεφαλή , kephalē means 'head'). The fine structure of the notochord and the cellular basis of its adult growth are best known for the Bahamas lancelet, Asymmetron lucayanum [ 51 ]
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The notochord plays an integral role in the development of the neural tube. Prior to neurulation, during the migration of epiblastic endoderm cells towards the hypoblastic endoderm, the notochordal process opens into an arch termed the notochordal plate and attaches overlying neuroepithelium of the neural plate. The notochordal plate then ...
The notochord will form the nucleus pulposus of intervertebral discs. There is some discussion as to whether these cells contributed from the notochord are replaced by others from the adjacent mesoderm. It gives rise to the notochordal process, which later becomes the notochord.
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Both Shh and HNF-3b transcripts are found in the notochord and the floor plate rostral to the node, and they are completely absent in the lateral and caudal neural plate and the primitive streak. In the node proper, the chordin expression pattern is very similar to that of HNF-3b, but more rostrally, chordin is no longer expressed in the floor ...