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HSAB is an acronym for "hard and soft (Lewis) acids and bases".HSAB is widely used in chemistry for explaining the stability of compounds, reaction mechanisms and pathways. It assigns the terms 'hard' or 'soft', and 'acid' or 'base' to chemical species.
A Lewis base is also a Brønsted–Lowry base, but a Lewis acid does not need to be a Brønsted–Lowry acid. The classification into hard and soft acids and bases ( HSAB theory ) followed in 1963. The strength of Lewis acid-base interactions, as measured by the standard enthalpy of formation of an adduct can be predicted by the Drago–Wayland ...
Ralph Gottfrid Pearson (January 12, 1919 – October 12, 2022) was an American physical inorganic chemist best known for the development of the concept of hard and soft acids and bases (HSAB). He received his Ph.D. in physical chemistry in 1943 from Northwestern University , and taught chemistry at Northwestern faculty from 1946 until 1976 ...
In chemistry, an acid–base reaction is a chemical reaction that occurs between an acid and a base.It can be used to determine pH via titration.Several theoretical frameworks provide alternative conceptions of the reaction mechanisms and their application in solving related problems; these are called the acid–base theories, for example, Brønsted–Lowry acid–base theory.
The hard/soft acid/base principle is utilized to predict molecular interactions and reaction direction. In general, interactions between molecules of the same type are preferred. That is, hard acids will associate with hard bases, and soft acids with soft bases.
They form stable products with hard bases, which are bases with ionic bonds. They target molecules such as phospholipids, nucleic acids, and ATP. Class B metals are metals that form soft acids. [2] Soft acids are acids with relatively covalent bonds. These metals, such as lead, gold, palladium, platinum, mercury, and rhodium, would rather bond ...
Later, Pearson proposed the theory of hard and soft acids and bases (HSAB theory). [27] In this classification, class A metals are hard acids and class B metals are soft acids. Some ions, such as copper(I), are classed as borderline. Hard acids form stronger complexes with hard bases than with soft bases.
Before we explain this incorrectness, let us examine a little of the principles of HSABs: Pearson is the one who created the HSAB theory, based on the principle: Hard acids can react well with hard bases, amd soft acids with soft bases. The following is a table of common HSABs. Blnguyen (bananabucket) 03:53, 21 November 2006 (UTC)