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The AHAAH model was first developed in 1987 by the U.S. Army Human Engineering Laboratory (HEL), which later became part of the U.S. Army Research Laboratory (ARL), to investigate the complex interactions between the outer, middle, and inner ears and understand the process behind hearing loss on the level of the cochlea.
The Vacanti mouse was a laboratory mouse that had what looked like a human ear grown on its back. The "ear" was actually an ear-shaped cartilage structure grown by seeding cow cartilage cells into a biodegradable ear-shaped mold and then implanted under the skin of the mouse; then the cartilage naturally grew by itself. [71]
The inner ear (internal ear, auris interna) is the innermost part of the vertebrate ear. In vertebrates , the inner ear is mainly responsible for sound detection and balance. [ 1 ] In mammals , it consists of the bony labyrinth , a hollow cavity in the temporal bone of the skull with a system of passages comprising two main functional parts: [ 2 ]
[6] [7] [note 1] Under ideal laboratory conditions, humans can hear sound as low as 12 Hz [8] and as high as 28 kHz, though the threshold increases sharply at 15 kHz in adults, corresponding to the last auditory channel of the cochlea. [9] The human auditory system is most sensitive to frequencies between 2,000 and 5,000 Hz. [10]
The human ear is made up of three areas: the outer, middle and inner ear. Within the inner ear sits the cochlea. The cochlea is a snail-shaped formation that enables sound transmission via a sensorineural route, rather than through a conductive pathway. [11] The cochlea is a complex structure, consisting of three layers of fluid.
hearing and balance (the ear, which includes the auditory system and vestibular system) smell (the nose) taste (the tongue) The distinction between special and general senses is used to classify nerve fibers running to and from the central nervous system – information from special senses is carried in special somatic afferents and special ...
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The outer ear funnels sound vibrations to the eardrum, increasing the sound pressure in the middle frequency range. The middle-ear ossicles further amplify the vibration pressure roughly 20 times. The base of the stapes couples vibrations into the cochlea via the oval window , which vibrates the perilymph liquid (present throughout the inner ...