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Azithromycin has beneficial effects in the treatment of asthma. It possesses antibacterial, antiviral, and anti-inflammatory properties which contribute to its effectiveness. Asthma exacerbations can be caused by chronic neutrophilic inflammation, and azithromycin is known to reduce this type of inflammation due to its immunomodulatory properties.
Phototoxicity, also called photoirritation, is a chemically induced skin irritation, requiring light, that does not involve the immune system. [1] It is a type of photosensitivity. [1] [2] The skin response resembles an exaggerated sunburn.
Para-aminobenzoic acid , found in some sunscreens, can also cause photosensitivity. Upon exposure to light, notably light containing ultraviolet radiation, discolouration of the skin (whether as inflammation, lightening or darkening) or rashes may result. In extreme cases, blistering may also occur.
Drug-induced photosensitivity Photosensitive drug reaction secondary to medications may cause phototoxic, photoallergic, and lichenoid reactions, and photodistributed telangiectasias , as well as pseudoporphyria.
With multiple sclerosis, inflammation settles in the central nervous system after immune cells attack the coating on nerves; lupus can cause inflammation in the heart, brain, kidney, and other organs.
Some photosensitizing agents, such as St. John's Wort, appear to increase the incidence of inflammatory skin conditions in animals and have been observed to slightly reduce the minimum tanning dose in humans. [34] [35] Some examples of photosensitizing medications (both investigatory and approved for human use) are: St. John's Wort [35] 9-me-bc ...
Photosensitivity is the amount to which an object reacts upon receiving photons, especially visible light. In medicine, the term is principally used for abnormal reactions of the skin, and two types are distinguished, photoallergy and phototoxicity .
The patient should be thoroughly questioned regarding any symptoms of connective tissue disorder, which may be the underlying pathology of the photosensitivity. Recent reports suggest that a connective tissue disorder may be a predisposing factor in patients using nonsteroidal anti-inflammatory drugs (NSAIDs) who develop pseudoporphyria.